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"No one could have predicted the Kardashians' and Jenners' success. But when you spend time with them, what resonates is the family unit. There are so many things about them that are glamorous, crazy, and unlike our lives, but the sense of family is universal. They love and stand by one another no matter what," says Ryan Seacrest, the executive producer of Keeping Up With the Kardashians and the family's self-described "big brother" in Cosmo's November 2015 issue, which celebrates the magazine's 50th birthday. "Their unvarnished candor reveals how close they really are. What's more, they present acceptance. You look at Bruce and now Caitlyn — you see the power of a family to come together when it would be so easy to fall apart. There's comfort in viewing that steadfastness of love." 

This cover is the ladies' first all together since 2011; stay tuned to see even more covers with individual photos, stories from the sisters, behind-the-scenes videos, and more!

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See the full Kardashians spread in the November 2015 issue of Cosmopolitan, on newsstands Oct. 13. Click here to subscribe to the digital edition!